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Journal Articles

Organ-on-Chip Devices Toward Applications in Drug Development and Screening

Christopher Uhl, Wentao Shi, Yaling Liu
Journal: Journal of Medical Devices
Article Type: Review Articles
J. Med. Devices. December 2018, 12(4): 040801.
Paper No: MED-18-1028
DOI: https://doi.org/10.1115/1.4040272
Published Online: September 21, 2018
View Article titled, Organ-on-Chip Devices Toward Applications in Drug Development and Screening
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Topics: Drugs, Hydrogels, Liver, Lung, Microfluidics, Physiology, Tumors, Manufacturing, Testing, Vessels
Journal Articles

Special Issue: Microscale Medical Devices

Yaling Liu
Journal: Journal of Medical Devices
Article Type: Guest Editorial
J. Med. Devices. December 2018, 12(4): 040301.
Paper No: MED-18-1112
DOI: https://doi.org/10.1115/1.4040996
Published Online: September 21, 2018
View Article titled, Special Issue: Microscale Medical Devices
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Topics: Medical devices, Microscale devices
Journal Articles

Finite Element Analysis of the Implantation Process of Overlapping Stents

Jiang Xu, Jie Yang, Salman Sohrabi, Yihua Zhou, Yaling Liu
Journal: Journal of Medical Devices
Article Type: Research-Article
J. Med. Devices. June 2017, 11(2): 021010.
Paper No: MED-16-1286
DOI: https://doi.org/10.1115/1.4036391
Published Online: May 3, 2017
View Article titled, Finite Element Analysis of the Implantation Process of Overlapping Stents
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Topics: Stents, Pressure
Journal Articles

Numerical Simulation of Particle Transport and Deposition in the Pulmonary Vasculature

Salman Sohrabi, Junda Zheng, Ender A. Finol, Yaling Liu
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. December 2014, 136(12): 121010.
Paper No: BIO-14-1173
DOI: https://doi.org/10.1115/1.4028800
Published Online: December 1, 2014
View Article titled, Numerical Simulation of Particle Transport and Deposition in the Pulmonary Vasculature
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Topics: Flow (Dynamics), Geometry, Particulate matter, Lung
Proceedings Papers

Cell Adhesion on a Wavy Surface

Jia Hu, Yaling Liu
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A001, June 26–29, 2013
Paper No: SBC2013-14059
DOI: https://doi.org/10.1115/SBC2013-14059
View Paper titled, Cell Adhesion on a Wavy Surface
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Topics: Adhesion, Nanoscale phenomena, Dimensions, Nanofabrication, Tissue engineering
Proceedings Papers

Ultrasound Mediated Enhancement of Nanoparticle Uptake in PC-3 Cancer Cells

Antony Thomas, Paige Baldwin, Yaling Liu
Proc. ASME. NEMB2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, V001T01A003, February 4–6, 2013
Paper No: NEMB2013-93115
DOI: https://doi.org/10.1115/NEMB2013-93115
View Paper titled, Ultrasound Mediated Enhancement of Nanoparticle Uptake in PC-3 Cancer Cells
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Topics: Cancer, Nanoparticles, Ultrasound, Microbubbles, Cell membranes, Drug delivery systems, Food and Drug Administration, Frequency-domain analysis, Imaging, Permeability
Proceedings Papers

Modeling Adhesion of Micro/Nanoparticles Under Shear Flow for Nanomedicine Application

Yaling Liu, Samar Shah
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1267-1268, June 17–21, 2009
Paper No: SBC2009-206555
DOI: https://doi.org/10.1115/SBC2009-206555
View Paper titled, Modeling Adhesion of Micro/Nanoparticles Under Shear Flow for Nanomedicine Application
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Topics: Adhesion, Modeling, Nanomedicine, Nanoparticles, Shear flow, Cardiovascular system, Computational methods
Proceedings Papers

Tissue-Light Interaction During Monitoring of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry

Willard Hanson, Najma Abdollahzadeh, Yaling Liu, Bumsoo Han
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 351-352, June 17–21, 2009
Paper No: SBC2009-205517
DOI: https://doi.org/10.1115/SBC2009-205517
View Paper titled, Tissue-Light Interaction During Monitoring of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry
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Topics: Biological tissues, Cancer, Energy resources, Fluorescence, Heating, Lasers, Microwaves, Patient treatment, Quantum dots, Temperature measurement
Proceedings Papers

Characterization of Nanoparticle Distribution in Microcirculation Through a Microfluidics Device

Antony Thomas, Jifu Tan, Susan Perry, Yaling Liu
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1063-1064, June 22–25, 2011
Paper No: SBC2011-53943
DOI: https://doi.org/10.1115/SBC2011-53943
View Paper titled, Characterization of Nanoparticle Distribution in Microcirculation Through a Microfluidics Device
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Topics: Microfluidics, Nanoparticles, Drugs, Drug delivery systems, Particulate matter, Patient treatment
Proceedings Papers

A Hybrid Particle-Cell Model for Nanoparticle Targeted Delivery in Microcirculation

Yaling Liu, Jifu Tan, Antony Thomas
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 367-368, June 22–25, 2011
Paper No: SBC2011-53033
DOI: https://doi.org/10.1115/SBC2011-53033
View Paper titled, A Hybrid Particle-Cell Model for Nanoparticle Targeted Delivery in Microcirculation
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Topics: Nanoparticles, Particulate matter, Blood, Adhesion, Blood flow, Dynamics (Mechanics), Fluids, Biomedicine, Collisions (Physics), Deformation
Proceedings Papers

A Coupled Particle-Continuum Model of Nanoparticle Targeted Delivery Under Vascular Flow With Experimental Validation

Yaling Liu, Kytai Nguyen, Manohara Mariyappa, Soujanya Kona, Jifu Tan
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 75-76, June 16–19, 2010
Paper No: SBC2010-19035
DOI: https://doi.org/10.1115/SBC2010-19035
View Paper titled, A Coupled Particle-Continuum Model of Nanoparticle Targeted Delivery Under Vascular Flow With Experimental Validation
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Topics: Blood flow, Nanoparticles, Particulate matter, Flow (Dynamics), Convection, Diffusion (Physics), Drug delivery systems, Drugs, Shapes, Adhesion
Journal Articles

Ion Diffusion and DNA Stretching in an Open Nanofluidic System

Woon-Hong Yeo, Kyong-Hoon Lee, Qingjiang Guo, Yaling Liu, Xia You, John A. Stamatoyannopoulos, Jae-Hyun Chung
Journal: Journal of Nanotechnology in Engineering and Medicine
Article Type: Research Papers
J. Nanotechnol. Eng. Med. February 2011, 2(1): 011004.
DOI: https://doi.org/10.1115/1.4003029
Published Online: January 4, 2011
View Article titled, Ion Diffusion and DNA Stretching in an Open Nanofluidic System
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Topics: Diffusion (Physics), DNA, Nanofluidics, Electrolytes, Shades and shadows, Fluorescence
Proceedings Papers

Characterization of Biosensor Detection Process at Ultra-Low Concentration Through a Stochastic Particle Model

Samar Shah, Yaling Liu, Walter Hu
Proc. ASME. NEMB2010, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, 13-14, February 7–10, 2010
Paper No: NEMB2010-13069
DOI: https://doi.org/10.1115/NEMB2010-13069
View Paper titled, Characterization of Biosensor Detection Process at Ultra-Low Concentration Through a Stochastic Particle Model
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Topics: Biosensors, Particulate matter, Sensors, Biomedicine, Cancer, Design, Diffusion processes, Diseases, Drugs, Electrodes
Proceedings Papers

Modeling DNA Translocation Kinetics in Nanopores With Selectivity

Abhijit Ramachandran, Qingjiang Guo, Samir Iqbal, Yaling Liu
Proc. ASME. NEMB2010, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, 267-268, February 7–10, 2010
Paper No: NEMB2010-13074
DOI: https://doi.org/10.1115/NEMB2010-13074
View Paper titled, Modeling DNA Translocation Kinetics in Nanopores With Selectivity
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Topics: DNA, Modeling, Nanopores, Manufacturing, Nanotechnology
Proceedings Papers

Modeling Targeted Drug Delivery in a Vascular Network

Yaling Liu, Kytai Nguyen, Manohara Mariyappa, Samar Shah, Jifu Tan
Proc. ASME. NEMB2010, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, 363-364, February 7–10, 2010
Paper No: NEMB2010-13075
DOI: https://doi.org/10.1115/NEMB2010-13075
View Paper titled, Modeling Targeted Drug Delivery in a Vascular Network
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Topics: Damage, Drug delivery systems, Modeling, Nanomedicine, Nanoparticles, Transportation systems
Proceedings Papers

A Hybrid Model for Nanoparticle Targeted Delivery in Blood Flow

Yaling Liu, Jifu Tan, Samar Shah
Proc. ASME. NEMB2010, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, 307, February 7–10, 2010
Paper No: NEMB2010-13253
DOI: https://doi.org/10.1115/NEMB2010-13253
View Paper titled, A Hybrid Model for Nanoparticle Targeted Delivery in Blood Flow
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Topics: Blood flow, Nanoparticles, Blood, Fluids, Erythrocytes, Fluid-dynamic forces, Platelets, Proteins
Proceedings Papers

Influence of Nanoparticle Design on Binding Efficiency

Yaling Liu, Samar Shah, Walter Hu, Jinming Gao
Proc. ASME. NEMB2010, ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, 265-266, February 7–10, 2010
Paper No: NEMB2010-13073
DOI: https://doi.org/10.1115/NEMB2010-13073
View Paper titled, Influence of Nanoparticle Design on Binding Efficiency
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Topics: Design, Nanoparticles, Adhesion, Dynamics (Mechanics), Shapes, Biomedical imaging, Blood flow, Cancer, Cardiovascular system, Drug delivery systems
Proceedings Papers

A Mesoscale Model for Molecular Interaction in Functionalized Nanopores

Yaling Liu, Samir M. Iqbal
Proc. ASME. IMECE2008, Volume 12: Mechanics of Solids, Structures and Fluids, 151-153, October 31–November 6, 2008
Paper No: IMECE2008-68542
DOI: https://doi.org/10.1115/IMECE2008-68542
View Paper titled, A Mesoscale Model for Molecular Interaction in Functionalized Nanopores
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Topics: Nanopores, DNA, Computer simulation, Design, Electric fields, Particle dynamics, Signals, Surface properties, Surface roughness
Proceedings Papers

Ion Diffusion Upon Concentrations in Open Nanofluidic Channels

Chen-Ling Chang, John Guofeng Bai, Kyong-Hoon Lee, Jae-Hyun Chung, Yaling Liu, Wing Kam Liu
Proc. ASME. IMECE2007, Volume 11: Micro and Nano Systems, Parts A and B, 913-918, November 11–15, 2007
Paper No: IMECE2007-42362
DOI: https://doi.org/10.1115/IMECE2007-42362
View Paper titled, Ion Diffusion Upon Concentrations in Open Nanofluidic Channels
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Topics: Diffusion (Physics), Nanofluidics, Flow (Dynamics), Fluids, Ions, Optical microscopes, Polishing equipment, Potassium
Proceedings Papers

Hybrid Fiber Fabrication Using an AC Electric Field and Capillary Action

Woonhong Yeo, Jae-Hyun Chung, Kyong-Hoon Lee, Yaling Liu, Wing Kam Liu
Proc. ASME. IMECE2007, Volume 11: Micro and Nano Systems, Parts A and B, 267-272, November 11–15, 2007
Paper No: IMECE2007-42305
DOI: https://doi.org/10.1115/IMECE2007-42305
View Paper titled, Hybrid Fiber Fabrication Using an AC Electric Field and Capillary Action
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Topics: Capillarity, Electric fields, Fibers, Manufacturing, Nanowires, Single-walled carbon nanotubes, Nanofibers, Binders (Materials), Bridges (Structures), Compression