..., including methylecgonidine, tropine, 3α-acetoxytropane, ecgonine methyl ester, cuscohygrine, N-norbenzoyltropine, benzoyltropine, hexanoylecgonine methyl ester, cocaine, cis -cinnamoylcocaine, and trans -cinnamoylcocaine. Methylecgonidine was determined to be the primary constituent and not an analytical...

...SD McDermott, PhD; JD Power, MSc A case study is presented where a woman travelling from South America to the Republic of Ireland was detained at Dublin Airport and articles of clothing she had in her luggage were found to be impregnated with cocaine. The study shows that the amount of powder...

...JF Casale, BS; JR Ehleringer, PhD; DR Morello, BS; MJ Lott, BS The forensic application of stable isotope analysis to cocaine and heroin for geolocation of exhibits must take into account the possible enrichment and/or depletion of 13 C and 15 N during the illicit manufacturing process. Continuous...

... more likely to have evidence of drug abuse than are victims of a motor vehicle collision. KEYWORDS: forensic science, forensic pathology, drug abuse, cocaine, death A few times every year our of ce investigates the death of a young adult with a history of drug abuse who has died suddenly...

...J Swiatko, BS; PR De Forest, D Crim; MS Zedeck, PhD The presence of cocaine in illicit drug samples is still being determined in some laboratories using spot tests and microcrystal tests. Seventeen chemical species were tested using three different spot tests (Wagner, Marquis, and cobalt...

... at a concentration of 0.05% (w/v), and benzoylecgonine (a cocaine metabolite) was also confirmed at a concentration of 0.43 mg/L by specific analysis using gas chromatography/mass spectrometry (GC/MS). These results enabled the pathologist to record the cause of death as intracerebral hemorrhage due to acute cocaine...

.... With quantitative GC-MS, the positive predictive value of oral fluid was 98, 92, and 90% for amphetamines, cocaine, and cannabis respectively. The prevalence of opiate positives was low. The SAMHSA cut-off values for oral fluid testing at the workplace, proved their usefulness in this study. The positive predictive...

...C Furnari, Chem.D.; V Ottaviano, Ph.D.; G Sacchetti, M.D.; M Mancini, M.D. A 27-year-old man was carrying in his digestive tract 99 packages each containing about 10 g of a 86% cocaine powder. The courier died by acute cocaine intoxication due to inflation and rupture of four packages during...

...RE Winecker, Ph.D.; BA Goldberger, Ph.D.; IR Tebbett, Ph.D.; M Behnke, M.D.; FD Eyler, Ph.D.; JL Karlix, Pharm.D.; K Wobie, M.A.; M Conlon, Ph.D.; D Phillips, Ph.D.; RL Bertholf, Ph.D. A method was developed for measuring cocaine and its metabolites, benzoylecgonine, ecgonine methyl ester...

... analysis of methamphetamine, amphetamine, MDA, MDMA, MDEA, and cocaine in seized drugs. The methodology uses a 32 cm by 50 μm capillary (length to detector 23.5 cm) with a commercially available buffer kit and diode array UV detection. Dynamic coating of the capillary surface is accomplished by flushing...

...H Ishii, B.S.; M Morishita; H Yamad; S Iwasa; T Yajima Most illicit cocaine is adulterated with other substances such as sugars and polyhydric alcohols or local anesthestics. Various sugars have been detected in seized cocaine. Analysis of sugars, polyhydric alcohols, and cocaalkaloids yields...

... pear, confirmed the presence of cocaine. This multidisciplinary approach is often necessary when there is a possible health risk to the public and rapid response is important. With this approach, it was quickly determined which drugs or poisons were used in this tampering. forensic science...

...KS Kalasinsky, Ph.D.; TZ Bosy, Ph.D.; GA Schmunk, M.D.; L Ang, M.D.; V Adams, M.D.; SB Gore; J Smialek, M.D.; Y Furukawa, M.D.; M Guttman, M.D.; SJ Kish, Ph.D. We measured concentrations of cocaine and its major metabolites (benzoylecgonine, ecgonine methylester, norcocaine, and cocaethylene) in 15...

...PA Hays, B.S.; GS Remaud, Ph.D.; É Jamin, Ph.D.; Y-L Martin, Ph.D. SNIF-NMR® (Site-specific natural isotopic fractionation measured by deuterium NMR) was employed on 36 heroin samples from seven different known origins, and two cocaine samples from two different known origins. Heroin has two...

... programs. The detection of cocaine in human hair using a commercially available micro-plate enzyme immunoassay is described for the first time. Sample size and incubation time were the major variables in the optimization of the method. In order to validate the procedure, the method was applied to 105...

...), sodium (Na), nickel (Ni), lead (Pb), strontium (Sr) and zinc (Zn), were determined in 46 cocaine samples confiscated by the Spanish police in Galicia (northwest Spain). Classification of these cocaine samples according to their geographic origin (Colombia and Venezuela) was achieved by the application...

... aortic dissections with particular emphasis on the role of drugs. Previous case reports have associated aortic dissections with both cocaine and methamphetamine intoxication. We found that seven of the 35 cases tested for drugs of abuse were positive for methamphetamine. Our study had no cases of solely...

... cocaine abuse. At autopsy, suspicious needle marks were noted on the right lower extremity. The lungs were of increased weight at 1000 and 1090 g and appeared edematous. The heart weighed 520 g and had a normal red-brown myocardium. Upon sectioning, a broken hypodermic needle of very small caliber...

...D Garside, Ph.D.; JD Ropero-Miller, B.A.; BA Goldberger, Ph.D.; WF Hamilton, M.D.; WR Maples, Ph.D. Fingernail and toenail specimens were obtained from 18 suspected cocaine users. The nails were cut, heated under methanolic reflux, and the methanolic extracts were purified by solidphase extraction...

...AS Krawczeniuk, M.S.; VA Bravenec, B.S. A free zone capillary electrophoresis method was developed for the quantitation of cocaine in illicit powders. The method uses a 75 mM sodium phosphate-sodium borate pH 8.5 buffered system and separates the most common cocaine adulterants and impurities...