Abstract

For evaluating the HIV 1 / HIV 2 Testpack (Abbott, Chicago, IL) to detect antibodies to human immunodeficiency virus (HIV) in whole postmortem blood 456 samples were collected prior forensic autopsies. All samples were tested using the enzymelinked immunoassay (ELISA) and the Testpack; positively reactive samples and samples with equivocal results were confirmed by Western blot. Of the 456 samples 21 (4.6 per cent) proved to be reactive in both systems (confirmed by Western blot). In 17 cases (3.7 percent) interpretation of the result was difficult, but no serious misinterpretations occurred.

It is concluded that the HIV-Testpack provides accurate results in testing whole postmortem blood for HIV antibodies.

References

1.
World Health Organization, Acquired Immunodeficiency Syndrome (AIDS)—Data as at 30 June 1993
,
Weekly Epidemiological Record
 0049-8114, Vol.
68
,
1993
, pp.
193
-
200
.
2.
Püschel
,
K.
,
Benz
,
D.
,
Betz
,
P.
,
Birkholz
,
M.
,
Brettel
,
H.-F.
,
Eidam
,
J.
,
Gerling
,
I.
, et al
,
HIV-1-Prävalenz bei Drogentoten in der Bundesrepublik Deutschland sowie im internationalen Vergleich (Stand 31.12.1991)
,
Rechtsmedizin
, Vol.
3
, No.
2
,
1993
, pp.
40
-
43
.
3.
Constantine
,
N. T.
,
Callahan
,
J. D.
, and
Watts
,
D. M.
,
Retroviral Testing: Essentials for Quality Control and Laboratory Diagnosis
,
CRC Press, Inc.
,
Boca Raton, FL
,
1992
.
4.
Li
,
L.
,
Constantine
,
N. T.
,
Zhang
,
X.
, and
Smialek
,
J. E.
, “
Determination of Human Immunodeficiency Virus Antibody Status in Forensic Autopsy Cases Using a Rapid and Simple FDA-Licensed Assay
,”
Journal of Forensic Sciences
 0022-1198, Vol.
38
, No.
4
,
1993
, pp.
798
-
805
.
5.
Jorgensen
,
A. J.
,
Dessau
,
K. B.
,
Klarholt
,
E.
,
Mouritz-Andersen
,
H. T.
, “
Reproducibility of a Rapid Test for HIV Antibody
,”
Ungeskr. Laeger
, Vol.
153
, No.
28
,
1991
, pp.
2007
-
2008
.
6.
Kelen
,
G. D.
,
Bennecoff
,
T. A.
,
Kline
,
R.
,
Green
,
G. B.
, and
Quinn
,
T. C.
, “
Evaluation of Two Rapid Screening Assays of the Detection of Human Immundeficiency Virus-1 Infection in Emergency Department Patients
,”
American Journal of Emergency Medicine
 0735-6757, Vol.
9
, No.
5
,
1991
, pp.
416
-
420
.
7.
Lyons
,
S. F.
, “
Evaluation of Rapid Enzyme Immunobinding Assays for the Detection of Antibodies to HIV-1
,”
South African Medical Journal
 0038-2469, Vol.
83
, No.
2
,
1993
, pp.
115
-
117
.
8.
Penning
,
R.
,
Tutsch-Bauer
,
E.
,
Beer
,
G.
,
Gürtler
,
L.
, and
Spann
,
W.
HIV-Infektion bei gerichtlichen Leichenöffnungen
,”
Beiträge zur gerichtlichen Medizin
, Vol.
47
,
1989
, pp.
23
-
29
.
9.
Penning
,
R.
,
Karmann
,
B.
,
Beer
,
G.
,
Gürtler
,
L.
, and
Spann
,
W.
, “
Prävalenz der HIV-Infektion bei gerichtlich Obduzierten und speziell Drogentoten am Institut für Rechtsmedizin der Universität München von 1985–1988
,”
Aids-Forschung
, Vol.
9
,
1989
, pp.
459
-
495
.
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