Technical Brief

Nonlocal Effect on Stiffness Measurements of a Collagen Molecule

[+] Author and Article Information
Victor Birman

Fellow ASME
Engineering Education Center,
Missouri University of Science and Technology,
12837 Flushing Meadows Dr., Suite 210,
St. Louis, MO 63131
e-mail: vbirman@mst.edu

Manuscript received November 16, 2014; final manuscript received January 13, 2015; published online January 23, 2015. Assoc. Editor: Taher Saif.

J. Appl. Mech 82(3), 034502 (Mar 01, 2015) (3 pages) Paper No: JAM-14-1520; doi: 10.1115/1.4029607 History: Received November 16, 2014; Revised January 13, 2015; Online January 23, 2015

Accurate modeling of collagen molecules including their stiffness is essential for our understanding of mechanics of collagen fibers and tissues where these fibers play a prominent role. Studies of mechanical properties of collagen molecules employing various experimental methods and molecular dynamics (MD) simulations yield a broad range of values of the modulus of elasticity. The effect of nonlocal elasticity on the molecule stiffness derived from experiments and simulations is assessed in this brief. The estimate of the correction accounting for the nonlocal effect utilizes the exact solution of the nonlocal elasticity theory for one-dimensional elastic bars. It is demonstrated that the effect of nonlocal elasticity on the stiffness of collagen molecules can be neglected.

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