Knee menisci are semi-lunar, fibrocartilaginous structures that convert applied compressive loads to circumferential hoop stresses which are attenuated at the tibial plateau via the meniscal attachments . These specialized interfaces, located at the lateral anterior (LA), lateral posterior (LP), medial anterior (MA), and medial posterior (MP) horns, are crucial to maintaining mechanical functionality of menisci, thereby preventing osteoarthritis . Soft-tissues subjected to compression and shear loads are known to possess proteoglycans, which aid in resisting these applied stresses by retaining interstitial fluid . Interestingly, proteoglycans are also known to be present at the meniscus to bone interface . Despite the presence of these biphasic attachments and their important role in joint load transfer, there have been no quantitative investigations of the mechanical environment within these attachments under physiological and pathological loads. Recent development of a novel pressure microsensor now allows direct observation of fluid pressure, which will aid in understanding the internal mechanical environment within the attachment sites. Previous work indicates that the attachment sites are geometrically, mechanically, and histologically different , thus it is hypothesized that the fluid pressures would likewise differ.
- Bioengineering Division
Internal Pressure of the Human Meniscal Attachments During Physiological and Pathological Loading
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Abraham, AC, Kaufman, KR, & Haut Donahue, TL. "Internal Pressure of the Human Meniscal Attachments During Physiological and Pathological Loading." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 451-452. ASME. https://doi.org/10.1115/SBC2012-80742
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