Coronary Heart Disease is the leading cause of death in the United States and was responsible for approximately one of every five deaths in 2003 [1]. Unnecessary admissions to US Hospitals of patients with suspected Acute Coronary Syndrome (ACS) is estimated to cost about 12 billion dollars a year [2]. The earliest biochemical markers currently assayed do not appear in the blood for hours after the onset of chest pain; a rapid test for myocardial ischemia would help to expedite treatment and avoid unnecessary hospital admissions [3].

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