In this paper, a recently developed higher-order microplane (HOM) model for softening and localization is implemented within a isogeometric finite-element framework. The HOM model was derived directly from a three-dimensional discrete particle model, and it was shown to be associated with a high-order continuum characterized by independent rotation and displacement fields. Furthermore, the HOM model possesses two characteristic lengths: the first associated with the spacing of flaws in the material internal structure and related to the gradient character of the continuum; the second associated with the size of these flaws and related to the micropolar character of the continuum. The displacement-based finite element implementation of this type of continua requires C1 continuity both within the elements and at the element boundaries. This motivated the implementation of the concept of isogeometric analysis which ensures a higher degree of smoothness and continuity. Nonuniform rational B-splines (NURBS) based isogeometric elements are implemented in a 3D setting, with both displacement and rotational degrees-of-freedom at each control point. The performed numerical analyses demonstrate the effectiveness of the proposed HOM model implementation to ensure optimal convergence in both elastic and softening regime. Furthermore, the proposed approach allows the natural formulation of a localization limiter able to prevent strain localization and spurious mesh sensitivity known to be pathological issues for typical local strain-softening constitutive equations.