Scanning acoustic microscopy and depth sensing indentation are two techniques used for extracting Young's, shear, and indentation moduli as well as the hardness of materials. In this work, we have applied these techniques on Ni50Al50(at. %) and (Ni40,Pt10)Al50(at. %) single crystals oriented (1 0 0) and (1 1 1) to measure their Young's modulus by two different techniques of local measurement and also the hardness of these alloys. Quantitative measurements highlight that the addition of 10 at.% of platinum induces a 5% decrease of Young's modulus (from 195 to 184 GPa) homogeneously spread over the surface orientations investigated,an 8% decrease of the indentation modulus, and a 40% increase of hardness without orientation effect.