In this study both linearized and the exponential forms of the Phan-Thien–Tanner model (PTT) are used to simulate the peristaltic flow in a tube. The solutions are investigated under zero Reynolds number and infinitely long wavelength assumptions. Computational solutions are obtained for pressure rise and friction force. The results of the average chyme velocity in the small intestine show that the PTT model is in good agreement with the experimental results, as shown in Table 1. Also, the magnitude of pressure rise and friction force of the exponential PTT model are smaller than in linear PTT model for different values of flow rate. The peristaltic pumping and the augmented pumping are discussed for various values of the physical parameters of interest. The pressure rise and friction force of PTT were compared with other studies in both Newtonian and non-Newtonian cases.